Accessing epigenetic variation in the plant methylome
نویسندگان
چکیده
منابع مشابه
Accessing epigenetic variation in the plant methylome.
Cytosine DNA methylation is the addition of a methyl group to the 5' position of a cytosine, which plays a crucial role in plant development and gene silencing. Genome-wide profiling of DNA methylation is now possible using various techniques and strategies. Using these technologies, we are beginning to elucidate the extent and impact of variation in DNA methylation between individuals and/or t...
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Plant populations show phenotypic diversity, which may be caused by genetic and epigenetic variation. It has recently been shown that new epigenetic variants are generated at a higher rate than genetic variants and several studies have shown that epigenetic variation can be influenced by the environment. Although the heritability of environmentally induced epigenetic traits has gained increasin...
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Heritable variation in plant phenotypes, and thus potential for evolutionary change, can in principle not only be caused by variation in DNA sequence, but also by underlying epigenetic variation. However, the potential scope of such phenotypic effects and their evolutionary significance are largely unexplored. Here, we conducted a glasshouse experiment in which we tested the response of a large...
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Reproductive factors have been linked to both breast cancer and DNA methylation, suggesting methylation as an important mechanism by which reproductive factors impact on disease risk. However, few studies have investigated the link between reproductive factors and DNA methylation in humans. Genome-wide methylation in peripheral blood lymphocytes of 376 healthy women from the prospective EPIC st...
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Recently, there has been increased interest in understanding the role of epigenetic processes in ecology and evolution (e.g. Richards, 2006; Bossdorf et al., 2008; Johannes et al., 2008; Richards et al., 2010). We now know that some epigenetic marks are not reset each generation, but are faithfully transmitted across generations (Jablonka & Raz, 2009), that natural variation can exist not only ...
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ژورنال
عنوان ژورنال: Briefings in Functional Genomics
سال: 2014
ISSN: 2041-2649,2041-2657
DOI: 10.1093/bfgp/elu003